ONGOING RESEARCH

UNDER STIS COORDINATION

Collaborative ENTIS & Motherisk  study on metformine exposure during pregnancy.

 

ENTIS survey on the description of legal requirements and practical settings for collaborative ENTIS studies.

 

Use of antiepileptics during breastfeeding: review of the literature and analysis of the summary of product characteristics (SmPC).

 

Pharmacokinetics & pharmacodynamics of nifedipine in preterm labor.

 

Prediction of infant drug exposure to antidepressant through breastfeeding using population pharmacokinetic modeling and simulation.

 

Lactobank: use of population pharmacokinetic modeling to investigate the magnitude and determinants of drug excretion into breastmilk.

 

WITH STIS PARTICIPATION

 

Collaborative ENTIS work on adherence to pharmacotherapy during pregnancy - opportunities to improve maternal-fetal health.

 

Multicohort analysis on efavirenz safety during pregnancy  (MoChiV and SHCS, in collaboration with PENTA and ECS).

 

PUBLICATIONS

2016

Winterfeld U, Merlob P, Baud D, Rousson V, Panchaud A, Rothuizen LE, Bernard N, Vial T, Yates LM, Pistelli A, Ellfolk M, Eleftheriou G, de Vries LC, Jonville-Bera A-P, Kadioglu M, Biollaz J, Buclin T. Pregnancy outcome following maternal exposure to pregabalin may call for concern. Published online before print May 18, 2016, doi: http:/​/​dx.​doi.​org/​10.​1212/​WNL.​0000000000002767

Neurology 10.1212/WNL.0000000000002767.

 

Weisskopf E, Fumeaux CJ, Bickle Graz M, Harari MM, Epiney M, Tolsa CB, Rouiller S, Tolsa JF, Eap CB, Vial Y, Csajka C, Panchaud A. SSRI antidepressant use during pregnancy and the assessment of the risk-benefit ratio. Rev Med Suisse. 2016 Mar 16;12(510):561-6.

 

Baud D, Van Mieghem T, Musso D, Truttmann AC, Panchaud A, Vouga M. Clinical management of pregnant women exposed to Zika virus. Lancet Infect Dis. 2016 Apr 4. pii: S1473-3099(16)30008-1.

 

Corbel A, Baud D, Chaouch A, Beney J, Csajka C, Panchaud A. Utility of an Algorithm to Increase the Accuracy of Medication History in an Obstetrical Setting. PLoS One. 2016 Mar 21;11(3):e0151205.

 

Dao K, Chtioui H, Rothuizen LE, Diezi L, Prod'hom S, Winterfeld U, Buclin T, Livio F. Pharmacovigilance update. Rev Med Suisse. 2016 Jan 13;12(500):75-9.

 

Panchaud A, Di Paolo ER, Koutsokera A, Winterfeld U, Weisskopf E, Baud D, Sauty A, Csajka C. Safety of Drugs during Pregnancy and Breastfeeding in Cystic Fibrosis Patients. Respiration. 2016;91(4):333-48.

 

2015

Winterfeld U, Klinger G, Panchaud A, Stephens S, Arnon J, Malm H, te Winkel B, Clementi M, Pistelli A, Manakova E, Eleftheriou G, Merlob P, Kaplan YC, Buclin T, Rothuizen LE. Pregnancy outcome following maternal exposure to mirtazapine: a multicentre prospective study. J Clin Psychopharmacol. 2015;35(3):250-9.

 

Weber-Schoendorfer C, Oppermann M, Wacker E, Bernard N, Beghin D, Cuppers-Maarschalkerweerd B, Richardson JL, Rothuizen LE, Pistelli A, Malm H, Eleftheriou G , Kennedy D, Kadioglu Duman M, Meister R, Schaefer C. Pregnancy outcome after TNF-α inhibitor therapy during the first trimester. A prospective multicenter cohort study. Br J Clin Pharmacol. 2015;80(4):727-39.

 

Lupattelli A, Spigset O, Björnsdóttir I, Hämeen-Anttila K, Mårdby AC, Panchaud A, Juraski RG, Rudolf G, Odalovic M, Drozd M, Twigg MJ, Juch H, Moretti ME, Kennedy D, Rieutord A, Zagorodnikova K, Passier A, Nordeng H. Patterns and factors associated with low adherence to psychotropic medications during pregnancy--a cross-sectional, multinational web-based study.

Depress Anxiety. 2015;32(6):426-36.

 

Weisskopf E, Fischer CJ, Bickle Graz M, Morisod Harari M, Tolsa JF, Claris O, Vial Y, Eap CB, Csajka C, Panchaud A. Risk-benefit balance assessment of SSRI antidepressant use during pregnancy and lactation based on best available evidence.

Expert Opin Drug Saf. 2015;14(3):413-27.

 

Winterfeld U, Baud D, Panchaud A, Rothuizen L, Livio F, Stoller R, Buclin T. Exposition in utero au paracétamol et troubles du développement: des doutes insuffisants pour changer nos pratiques! pharmaJournal 23 | 11.2015: 11-12.

 

Winterfeld U, Baud D, Panchaud A, Rothuizen L, Livio F, Stoller R, Buclin T. Exposition in utero au paracétamol et troubles du développement: des doutes insuffisants pour changer nos pratiques! Bulletin Des Médecins Suisses – Schweizerische Ärztezeitung – Bollettino Dei Medici Svizzeri 2015;96(41):1494–1495.

 

2014

Winterfeld U, Rothuizen LE, Gotta V, Panchaud A, Rossetti AO, Buclin T. Anwendung von Antiepileptika bei Frauen im gebärfähigen Alter und in der Schwangerschaft: Vergleich der Fachinformationen in Deutschland und der Schweiz.

Der Nervenarzt. 2014 85(6):738-46.

 

Panchaud A, Weisskopf E, Winterfeld U, Baud D, Eap CB, Csajka C, Widmer N. Modifications pharmacocinétiques liées à la grossesse et place du suivi thérapeutique pharmacologique? Thérapie 2014,69(3):223-34.

 

Csajka C, Jaquet A, Winterfeld U, Meyer Y, Einarson A, Panchaud A. Risk perception by healthcare professionals related to drug use during pregnancy: a Swiss survey. Swiss Medical Weekly, 2014;144:w13936.

 

Weber-Schoendorfer C, Chambers C, Wacker E, Beghin D, Bernard N; on behalf of the network of French pharmacovigilance centers, Shechtman S, Johnson D, Cuppers-Maarschalkerweerd B, Pistelli A, Clementi M, Winterfeld U, Eleftheriou G, Pupco A, Kao K, Malm H, Elefant E, Koren G, Vial T, Ornoy A, Meister R, Schaefer C. Pregnancy outcome after rheumatologic methotrexate (MTX) treatment prior to or during early pregnancy: A prospective multicenter cohort study.

Arthritis Rheumatol. 2014;66(5):1101-10.

 

Lupattelli A, Spigset O, Twigg MJ, Zagorodnikova K, Mårdby AC, Moretti ME, Drozd M, Panchaud A, Hämeen-Anttila K, Rieutord A, Gjergja Juraski R, Odalovic M, Kennedy D, Rudolf G, Juch H, Passier A, Björnsdóttir I, Nordeng H. Medication use in pregnancy: a cross-sectional, multinational web-based study. BMJ Open. 2014 17;4(2).

 

2013

Winterfeld U, Allignol A, Panchaud A, Rothuizen LE, Merlob P, Cuppers-Maarschalkerweerd B, Vial T, Stephens S, Clementi M, De Santis M, Pistelli A, Berlin M, Eleftheriou G, Maňáková E, Buclin T. Author’s response to: Statins in pregnancy: safety and perspectives of therapeutic applications. BJOG. 2013;120(11):1440.

 

Winterfeld U, Allignol A, Panchaud A, Rothuizen LE, Merlob P, Cuppers-Maarschalkerweerd B, Vial T, Stephens S, Clementi M, De Santis M, Pistelli A, Berlin M, Eleftheriou G, Maňáková E, Buclin T. Pregnancy outcome after maternal exposure to statins: a multicenter prospective study. BJOG. 2013;120(4):463-71.

 

Weisskopf E, Lepigeon K, Baud D, Csajka C, Panchaud A. Médicaments tocolytiques : utilisation en cas de menace d’accouchement prématuré. pharmaJournal 2013; 19(9):5-7.

 

Weisskopf E, Lepigeon K, Fischer C, Morisod M, Bickle M, Eap CB., Tolsa JF., Vial Y, Csajka C, Panchaud A. Une étude multicentrique : antidépresseurs, grossesse et allaitement. Forum gynécologie suisse, 2013 ; 13(2):4-6.

 

Panchaud A, Berger J, Bugnon O. Médicaments, grossesse et allaitement. BabyGuide. Le manuel officiel suisse 2013 ; 31-33.

 

Panchaud A, Berger J, Csajka C, Bugnon O. Médicaments, grossesse et allaitement: toutes les sources d'information ne sont pas fiables! pharmaJournal, 2013; 1:15-16.

 

2012

Panchaud A, Csajka C, Merlob P, Schaefer C, Berlin M, De Santis M, Vial T, Ieri A, Malm H, Eleftheriou G, Stahl B, Rousso P, Winterfeld U, Rothuizen LE, Buclin T. Pregnancy Outcome Following Exposure to Topical Retinoids: A Multicenter Prospective Study. J Clin Pharmacol. 2012;52(12):1844-51.

 

Einarson A, Smart K, Vial T, Diav-Citrin O, Yates L, Stephens S, Pistelli A, Kennedy D, Taylor T, Panchaud A, Malm H, Koren G, Einarson TR. Rates of major malformations in infants following exposure to duloxetine during pregnancy: a preliminary report.

J Clin Psychiatry. 2012;73(11):1471.

 

Klieger-Grossmann C, Weitzner B, Panchaud A, Pistelli A, Einarson TR, Koren G, Einarson A. Escitalopram use in Pregnancy: an observational cohort study. J Clin Pharmacol. 2012;52(5):766-70.

 

Winterfeld U, Meyer Y, Panchaud A, Einarson A. Management of defective and insufficient lactation in Switzerland and Canada: a survey of midwives’ current practice. Breastfeeding Medicine. 2012;7:317-8.

 

Wettach C, Thomann J, Lambrigger-Steiner C, Buclin T, Desmeules J, von Mandach U. Pharmacovigilance in pregnancy: adverse drug reactions associated with fetal disorders. J Perinat Med. 2012;2;0(0):1-7.

 

Winterfeld U, Buclin T. Beratung und Dokumentation zur Arzneimittelanwendung in Schwangerschaft und Stillzeit. Pharmazeutische Medizin. 2012 2: 116-119.

 

Panchaud A, Verdun FR, Csajka C. Un examen radiologique est-il toujours à risque pour l’enfant à naître? Journal Suisse de Pharmacie 2012 n°17.

 

 

 

 

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Last update: 30.6.2016